A newborn with progeria looks healthy, but by the age of between 10 months and 24 months, features of accelerated aging start to appear.

Signs of progeria include:

• limited growth and short stature	• lack of body fat and muscle
• loss of hair, including eyelashes,eyebrows	• early signs of skin aging, including thin skin
• stiffness in the joints	• visible veins
• stroke	• narrow, wrinkled, or shrunken face
• a head that is large compared with the body	• a small jaw bone
• slow and abnormal tooth development	• a high-pitched voice
• limited motion range, possible hip dislocation	• generalized atherosclerosis, leading to cardiovascular and heart disease

The connective tissue in the skin tends to become tough and hardened.
Tests may also show signs of insulin resistance, but cholesterol and
triglyceride levels should be normal. Progeria does not impact the child's brain
development or intelligence, and it does not mean a higher risk of infection. It does not affect motor skills, so children with the condition can sit, stand, and walk like any other child. Children from any ethnic background can have progeria, but they will have a similar appearance.